INSIGHT
(what we need)

Nerve-stimulating therapies could soon replace drugs for the majority of chronic diseases. 

Electroceuticals – or devices that use electrical impulses to treat chronic ailments – come from a long history of bioelectronic medicine. Earlier versions of this include internal devices like a pace maker or a cochlear implant. There are also external applications that produce electrical activity to ‘jumpstart’ the body’s responses like a defibrillator or resynchronizer. But now that mapping of the brain has become more nuanced, targeted electrical impulses could become a mainstay of medical therapy and replace many of the chemical or surgical interventions that come with their host of side effects and out-of-commission timelines. 

A new frontier of “electronic neurostimulation” and “neuroimmune modulation” is underway, looking at non-invasive impulse therapies to effectively re-circuit neurosignaling in the body. There are those that treat the brain’s anatomical irregularities (like opening the blood-brain barrier for Alzheimers) and those that look at regulating signals in neural circuitry outside of the brain. Transcranial Magnetic Stimulation (TMS) is a non-invasive focused approach to treat depression, OCD and other neuropsychiatric disorders. TMS specifically targets parts of the brain that inhibit or release the neurotransmitters associated to your emotions, executive processing or feelings of pleasure. It doesn’t require surgery, skin prep, or long treatment times that would take someone away from work beyond a day or two. It’s currently approved by the FDA to treat major depressive disorders, obsessive compulsive disorder, migraines and smoking cessation. However, treatment is revealing it can go far and wide: from addictions to Schizophrenia, chronic pain to PTSD. Currently the Brain Stimulation Lab at Stanford is looking at the novel brain stimulation techniques and plethora of ailments they could solve. 

For less severe diseases or disorders, there are also therapies that address signaling irregularities that maintain the balance state of inflammatory pathways that might lead to debilitating diseases like rheumatoid arthritis (RA), psoriasis, and multiple sclerosis (MS) if left untreated. Innovations like Vagal Nerve Stimulation (VNS) are supporting the release of specific neurotransmitters to quiet the immune cells involved in inflammation. Other disturbed signaling causing an increase autoimmune conditions (like inflammatory bowel disease) are being researched for similar therapies, especially as existing chemical drugs are failing or causing severe side effects in patients. As rising gut health issues add a complexity to pharmaceutical interventions, the direct influence of electroceuticals is providing answers.  

By looking at the body’s own healing reflex to maintain homeostasis, we would no longer need to rely on chemical interventions (or frankly, big pharma) to run our lives. It could potentially help people through chronic pain, trauma or addiction (like opioid withdrawal) by decreasing symptom severity and help people function while retraining their nervous system signaling. This exciting frontier could perhaps eventually bridge the gap between targeted electrical signaling of the brain and nerves to the less specific “bioenergetic medicine” of the currently unmeasurable subtle energy body — and shift the mainstream focus from allopathic treatments to more measurable holistic treatments that in turn become less ‘alternative.’

INSPIRATION
(what we want)

SetPoint: tiny pulses to reset your immunological reflexes.

An electrical therapy designed to offer patients alternative treatment for chronic autoimmune diseases with less risk and lower cost than drug therapy. 

• Tiny implant that generates precise electrical pulses with dosing through an iPad application

• No pills or injections to miss

• Reduces the activity of several key intracellular inflammation pathways without being immunosuppressive. 

• Ongoing research through randomized, double-blind studies to treat patients with rheumatology issues. 

• Over a decade of proof-of-concept clinical studies have been conducted to evaluate the patient experience. 

INNOVATION
(what we wish for)

Worryless: decode your fear and anxiety with electroceuticals and psychosensory therapy to help you get out of your own way!

Imagine recoding your mind so that you can take more control of your life and go after your ambitions without doubt, fear, or anxiety.

• Electroceutical intervention through TMS pulses and psychosensory techniques (ie. Havening - as depicted) to reprogram fearful memories or anxiety-inducing thoughts.

• This ‘amygdala repotentiation therapy’ changes how our fear center in the brain processes emotions to feel safe and empowered rather than fearful or anxious. Can be applied to situations of past trauma (ie. stage fright caused by humiliation) or anxiety about the future (ie. receiving vitriol on social media for posting opinions).  

• Short non-invasive sessions that use imaginal recall and stress response detection to target the treatment to specific thoughts with a goal to bring the participant to zero distress with a previously traumatizing memory or perceived anxiety. 

• Eliminate the effects of trauma encoding by repetitive stress responses causing a cascade of chemical and electrical signaling in the body that dysregulate homeostatic processes.  

• Eliminate physical ailments (ie. back pain) that are tied to chronic unresolved emotions (ie. anger). 

  More on the proposed science behind for the interested.